An early marker of diabetes has been identified in adolescents with polycystic ovary syndrome

A scientific article published on 23 June in Nature Scientific Reports reveals that the oxidation of the amino acid methionine is a blood marker that indicates the oxidation of good cholesterol (HDL lipoproteins). This oxidation prevents the cholesterol from maturing and, therefore, from carrying out its protective function.


This study has been carried out in a group of 16-year-old girls in the initial stages of polycystic ovary syndrome, which can lead to a high risk of anovulatory infertility, type 2 diabetes, cardiovascular diseases and metabolic syndrome in adulthood.


The study shows that after a new 18-month-long combined pharmacological treatment the parameters of androgen excess and insulin resistance are restored. Also restored is the marker that has now been discovered to be associated with the risk of diabetes in adulthood.


The work was carried out by Ciberdem researchers working at the Centre for Omic Sciences at the Universitat Rovira i Virgili jointly with researchers from the Sant Joan de Déu Hospital in Barcelona.


You can find the complet article here.